Knee Joint Injections in Southern California

Find lasting relief from knee pain with image-guided joint injections at Integrative Sports & Spine. Our board-certified specialists use advanced techniques to reduce inflammation and improve mobility—so you can get back to the activities you love. Schedule your consultation today.

Quick Overview

con representing estimated treatment duration for pain procedures

15-30 Minutes

Treatment Time

In little as 15-30 mins, our team will expertly treat the source of your pain.

Recovery icon symbolizing average healing time after pain treatment

24-48 Hours

Recovery Time

Minimal downtime; resume normal activities within 24–48 hours

Location pin icon showing availability of pain treatments at all four Southern California clinics: Riverside, Alhambra, Long Beach, and City of Industry

All Clinics

Location Available

Available at all ISS clinics - Long Beach, Alhambra, Riverside, and City of Industry

What are Knee Joint Injections?

Knee joint injections are minimally invasive treatments used to relieve pain and inflammation caused by arthritis, injury, or chronic wear and tear. These injections deliver corticosteroids, hyaluronic acid, or regenerative therapies directly into the knee joint using imaging guidance to ensure precision and effectiveness.

They’re often recommended when conservative treatments like rest, physical therapy, or oral medications fail to provide sufficient relief.

Benefits of Knee Joint Injections

Direct Pain Relief

Medications are injected right into the knee joint to reduce inflammation and relieve stiffness from arthritis, overuse, or injury.

Enhances Joint Lubrication (with Gel Injections)

Hyaluronic acid injections help cushion and lubricate the joint, improving comfort and mobility, especially in moderate osteoarthritis.

Non-Surgical Option

Performed in under 30 minutes with no incisions, knee injections are ideal for patients looking to avoid surgery or extended downtime.

Customizable to Your Condition

Depending on your needs, we offer steroid, gel, or PRP injections—ensuring your treatment is tailored to your specific diagnosis and goals.

Conditions Treated with Knee Joint Injections

Knee OsteoarthritisAs cartilage in the knee wears down over time, it can cause pain, stiffness, and swelling. Injections help reduce joint inflammation and improve mobility, making daily tasks like walking and climbing stairs more manageable.

Meniscus Tears (Non-Surgical Cases)Small or degenerative meniscus tears can lead to pain and limited motion, especially in older adults. Injections help calm inflammation and support healing, often avoiding the need for surgical intervention.

Rheumatoid ArthritisAutoimmune-related joint inflammation can cause ongoing knee pain, swelling, and stiffness. Corticosteroid injections help suppress the immune response in the joint and reduce flare-ups.

Post-Traumatic Knee Pain or SwellingInjuries from sports, accidents, or overuse can cause inflammation inside the knee joint. Injections provide pain relief and reduce swelling to support recovery and rehabilitation.

Patellofemoral Pain SyndromeAlso known as “runner’s knee,” this condition involves pain at the front of the knee due to joint stress or misalignment. Injections can reduce inflammation around the kneecap and improve movement.

Bursitis or Tendonitis Around the KneeIrritation of the bursa or tendons near the knee joint can lead to localized pain, especially during activity. Targeted injections ease inflammation and discomfort, promoting a faster return to motion.

What to Expect

Before Your Treatment

Preparation Guidelines• Avoid anti-inflammatory medications for 1-2 weeks before treatment
• Stay hydrated and eat a healthy meal before your appointment
• Wear loose clothing for easy access to the knee

Initial ConsultationOur providers will review your symptoms, history, and imaging results to determine the most appropriate injection type and plan.

During the Procedure

Preparation• You’ll be positioned comfortably with the knee exposed and sterilized
• A local anesthetic is used to numb the area and minimize discomfort

Injection Process• Using ultrasound or fluoroscopic guidance, the physician will insert a thin needle into the joint
• The selected medication is injected directly into the knee space
• The procedure usually takes 15–30 minutes

After Your Treatment

Immediate Recovery• You will be monitored briefly before being discharged
• Some patients feel immediate relief, but the full benefits typically appear over several days

Patient applying ice pack after pain treatment as part of immediate recovery protocol

First 24-48 Hours• Rest and avoid heavy physical activity
• Apply ice to the injection site if needed for swelling or discomfort
• You may experience mild soreness or a temporary flare-up

Patient resting at home during the first 48 hours after a pain management procedure

Long-Term Recovery• Gradually resume normal activities as pain relief progresses
• Follow-up appointments will be scheduled to monitor your progress

Patient attending follow-up recovery session at a Southern California pain clinic for long-term pain relief

Why Choose Us for Knee Joint Injections?

Joint Pain Experts
Our board-certified specialists have extensive experience in treating knee pain caused by arthritis, injury, or degeneration. We stay up to date with the latest interventional techniques to ensure effective, long-lasting relief.

Precision-Guided Techniques
We use ultrasound or fluoroscopic imaging to guide each injection, allowing for pinpoint accuracy and maximum medication effectiveness—minimizing risk and improving results.

Customized Care for Long-Term Relief
Knee injections are often just one part of your care. We create personalized treatment plans that may include bracing, physical therapy, or regenerative medicine like PRP to support sustained improvement.

Trusted Across Southern California
With four easily accessible clinics in Long Beach, Alhambra, Riverside, and City of Industry, you’ll receive expert care close to home. Multilingual support and flexible scheduling are available.

Advanced pain management equipment used by specialists at our Southern California clinics in Riverside, Alhambra, Long Beach, and City of Industry

Frequently Asked Questions

How do I know if I’m a candidate for knee injections?

If you have knee pain from arthritis, injury, or inflammation that hasn’t improved with rest, physical therapy, or medications, you may benefit from injections. Imaging and a physical exam help confirm if this treatment is right for you.

What types of knee injections do you offer?

We offer corticosteroid injections for inflammation, hyaluronic acid (gel) injections for lubrication, and platelet-rich plasma (PRP) for regenerative healing. Your provider will recommend the best option for your condition.

Do the injections hurt?

Most patients describe the injection as a quick pinch or pressure. We use a local anesthetic and imaging guidance to keep discomfort to a minimum.

How long does pain relief last?

Relief can last anywhere from several weeks to several months, depending on the type of injection and severity of your condition. Some patients receive ongoing injections as part of a longer-term treatment plan.

Are there any side effects or risks?

Side effects are typically mild and short-term, such as soreness, swelling, or a temporary increase in pain. Serious complications are rare, especially when performed under imaging guidance.

Logos of major insurance providers accepted at our pain management clinics

Insurance Coverage

Integrative Sports & Spine works with most major insurance providers to ensure your treatment is accessible and affordable. Our team will verify coverage and review any potential out-of-pocket expenses before your visit.

We accept:
• Medicare
• PPO Plans
• Personal Injury
• Most Major Insurance Carriers
• Self-Pay Options Available

What Our Patients Say

Tina A., 59

Treated for knee osteoarthritis

I could barely walk without pain before. After my injection, I’m walking my dog again and even went on a hike.

Leo D., 47

Treated for post-injury knee pain

The entire process was smooth and professional. I felt a difference just days after the injection.

Martha P., 65

Treated for degenerative joint pain

I was nervous at first, but the doctor explained everything and it really helped. The results were better than I expected.

Ready to Start Your Healing Journey?

Get lasting knee joint pain relief with expert care at Integrative Sports & Spine. Schedule your consultation today to see if this advanced pain management solution is right for you.Get lasting joint pain relief with expert care at Integrative Sports & Spine. Schedule your consultation today to see if this advanced pain management solution is right for you.

Call (833) 476-7377 or complete our online form to request an appointment at any of our four Southern California locations.

Book an Appointment

Related Services

Epidural Steroid Injections

Epidural steroid injections complement facet joints injections by reducing inflammation around spinal nerves, enhancing overall pain relief.

View More
Radiofrequency Ablation (RFA)

RFA offers long-term relief by targeting the sensory nerves responsible for transmitting pain from inflamed facet joints. Often used after a successful diagnostic injection.

View More
Platelet-Rich Plasma (PRP) Therapy

PRP uses your body’s own growth factors to promote healing and reduce inflammation. It can complement facet joint injections for patients seeking natural regenerative support.

View More
Trigger Point Injection

Ideal for muscle pain caused by tight knots or spasms that often accompany spinal joint dysfunction. These injections help release tension and improve mobility.

View More
Contact Us

(833) 476-7377

Email Us

contact@issrehab.com

Open Hours

Mon - Fri: 9:00am to 5:00pm